Patents

Description

PROCEDEU PENTRU PURIFICAREA SI IZOLAREA NUCLEOZIDEI IMBUNATATITE IN ANOMER-BETA

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Interest:

Assignment

Publication info:

No.: RO118296

Date: 30.04.2003

Inventor(s):

CHOU TA SEN [US]

POTEET LAURIE MICHELLE [US]

KJELL DOUGLAS PATTON [US]

Applicant(s):
LILLY CO ELI [US]
Classification:
International patent classification (IPC):
C07H19/04; C07H19/06; C07H19/073
Cooperative patent classification (CPC):
C07H19/04 (EP, US); C07H19/06 (EP, KR, US); Y02P20/55 (EP, US)
Application info:
No.: RO19970000898
Date: 01.11.1995
Priority number(s):
US19940340972 17.11.1994 ; WO1995US14086 01.11.1995
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AR001045; ATE210142; AU4139396; AU702588; BG101485; BG62737; BR9509904; CA2205350; CN1044119; CN1165519; CO4600741; CZ148197; CZ292013; DE69524365; DK0712860; EP0712860; ES2164745; HU219019; HUT77926; IL115854; JPH10509170; KR100424990; KR970707143; MX9703548; MY115183; NO308305; NO972214; NZ296712; PE50196; PL182052; PL320634; PT712860; RU2161622; SI0712860; SK283160; SK48597; TW377356; UA53614; US5606048; WO9616072; YU49446; YU70995; ZA959321
Description:

Inventia se refera la un procedeu pentru purificarea si izolarea unei nucleozide imbogatite in anomer- beta, care cuprinde: a) obtinerea unui amestec continand R" si o nucleozida imbogatita in anomer-beta intr-un solvent cu punct de fierbere ridicat; b) diluarea amestecului cu un solvent organic; c) adaugarea amestecului de reactie peste solutia apoasa de acid si d) mentinerea amestecului de acid, astfel obtinut, la o temperatura cuprinsa intre 70 si 100 degree C pana precipita nucleozida imbunatatita in anomer-beta.

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