DERIVATI ANALOGI AI VITAMINEI D SI PROCEDEU PENTRU PREPARAREA ACESTORA

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Publication info:

No.: RO118286

Date: 30.04.2003

Inventor(s):

GRUE-SORENSEN GUNNAR [DK]

Applicant(s):
LEO PHARM PROD LTD [DK]
Classification:
International patent classification (IPC):
A61K31/00; A61K31/59; A61P17/00; A61P17/06; A61P17/10; A61P17/14; A61P19/00; A61P19/10; A61P25/28; A61P29/00; A61P3/00; A61P3/02; A61P3/10; A61P35/00; A61P37/00; A61P37/02; A61P9/00; A61P9/12; C07C401/00; C07C41/26; C07C43/13; C07D309/12; C07F7/18

Cooperative patent classification (CPC):
A61K31/59 (KR); A61P17/00 (EP); A61P17/06 (EP); A61P17/10 (EP); A61P17/14 (EP); A61P19/00 (EP); A61P19/10 (EP); A61P25/28 (EP); A61P29/00 (EP); A61P3/00 (EP); A61P3/02 (EP); A61P3/10 (EP); A61P35/00 (EP); A61P37/00 (EP); A61P37/02 (EP); A61P5/18 (EP); A61P9/00 (EP); A61P9/12 (EP); C07C401/00 (EP, KR, US)
Application info:
No.: RO19980000072
Date: 21.03.1997
Priority number(s):
GB19960007034 03.04.1996 ; WO1997DK00128 21.03.1997
Related patents:
ATE206394; AU2567097; AU713630; CN1075809; CN1196720; CZ290097; CZ898; DE69707121; DK0891326; EP0891326; ES2163144; HU9901600; JP2000508635; KR100478741; KR19990035844; NZ329531; PL186771; PL324635; PT891326; RU2169142; US5932565; WO9737972
Description:

Inventia se refera la derivati analogi ai vitaminei D, avand formula generala I: in care Q reprezinta un diradical hidrocarbilena C1-C8, R reprezinta hidrogen sau hidrocarbil C1-C6, sau douagrupe R, luate impreuna cu atomul de carbon care poarta grupa hidroxi, pot forma un inel carbociclic C3-C8; la un procedeu pentru prepararea acestora, la compusii intermediari, utilizati la prepararea derivatilor de vitamina D, la compozitiile farmaceutice care contin acesti compusi, precum si la utilizarea acestor derivati in tratamentul sau profilaxia bolilor caracterizate prin diferentierea anormala a celulelor si/sau proliferarea anormala a celulelor, ca psoriazis si cancer.

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