PROCEDEU DE OBTINERE A DERIVATILOR DE 4A, 5, 9, 10, 11, 12-HEXAHIDRO-6H-BENZOFURO 3A, 3, 2- EF 2 BENZAZEPINA SI INTERMEDIARI CARE INTERVIN IN PROCEDEU

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Interest:

Assignment

Publication info:

No.: RO118419

Date: 30.05.2003

Inventor(s):

LASZLO CZOLLNER [AT]

FROHLICH JOHANNES [AT]

JORDIS ULRICH [AT]

KUENBURG BERNHARD [AT]

Applicant(s):
WALDHEIM PHARMAZEUTIKA GMBH [AT]
Classification:
International patent classification (IPC):
C07B53/00; C07B57/00; C07C217/58; C07D223/00; C07D307/00; C07D491/00; C07D491/048; C07D491/06; C07D491/10; C07D491/153; C07D491/20

Cooperative patent classification (CPC):
C07D491/10 (EP, US)
Application info:
No.: RO19970000721
Date: 23.10.1995
Priority number(s):
AT19940001980 21.10.1994 ; US19950487102 07.06.1995 ; WO1995AT00208 23.10.1995
Related patents:
ATE188460; AU3693895; AU695352; BG101417; BG62133; BR9509406; CA2203183; CN1069624; CN1170395; CZ119597; CZ295528; DK0787115; EP0787115; ES2106700; FI114477; FI971609; GR3032965; GR980300015; HU217207; HUT77716; JP4187786; JPH10507457; KR100352212; MX9702892; NO313234; NO971645; NO971796; NZ294191; PL184590; PL319754; PT787115; RU2146258; SI0787115; SK283877; SK48397; US6043359; WO9612692
Description:

Inventia prezinta un procedeu pentru obtinerea derivatilor de 4a, 5, 9, 10, 11, 12-hexahidro-6H-benzofuro 3a, 3,2-ef 2 benzazepina cu formula I: si, in special, pentru obtinerea de galantamina cu formula II: in forma cristalina si de puritate ridicata. Procedeul este condus cu randamente ridicate atat pe faze, cat si in ansamblu, si poate fi utilizat la scara industriala.

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