Patents

Description

MONOMETANSULFONAT DE ACID (E)-ALFA-[2-N-BUTIL-1-[(4-CARBOXIFENIL)METIL]-1H-IMIDAZOL-5-IL]METILEN-2-TIOFENPROPIONIC, PROCEDEE DE PREPARARE ŞI COMPOZIŢII FARMACEUTICE

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Interest:

Assignment

Publication info:

No.: RO118870

Date: 30.12.2003

Inventor(s):

PALEPU NAGESWARA R [GB]

VENKATESH GOPADI M [US]

DUDDU SARMA [US]

Applicant(s):
SMITHKLINE BEECHAM CORP [US]
Classification:
International patent classification (IPC):
A61K31/00; A61K31/135; A61K31/138; A61K31/40; A61K31/401; A61K31/415; A61K31/4164; A61K31/4178; A61K31/44; A61K31/4409; A61K31/4433; A61K31/54; A61K31/635; A61K38/55; A61K45/00; A61P13/00; A61P13/12; A61P43/00; A61P9/00; C07D233/02; C07D233/04; C07D233/54; C07D409/06
Cooperative patent classification (CPC):
A61K31/415 (EP); A61K31/4178 (EP); A61K31/44 (EP); A61K31/54 (EP); A61K31/635 (EP); A61K38/556 (EP); A61P13/00 (EP); A61P13/12 (EP); A61P43/00 (EP); A61P9/00 (EP); A61P9/04 (EP); A61P9/10 (EP); A61P9/12 (EP); C07D409/06 (EP); A61K31/415; A61K31/35; A61K2300/00; A61K31/44; A61K31/54; A61K31/635; A61K38/556
Application info:
No.: RO19980001406
Date: 26.03.1997
Priority number(s):
US19960014414P 29.03.1996 ; WO1997US04877 26.03.1997
Related patents:
AP901; AR006439; ATE239723; AU2547097; AU726694; BG102822; BG64095; BR9708336; CA2250395; CN1214682; CN1332167; CZ293345; CZ310198; DE69721749; DK0889880; DZ2199; EA001958; EA199800873; EG23889; EP0889880; ES2198564; HK1016594; HU228263; HU9902769; ID16507; JP2000508632; JP4316013; MA24437; MY117682; NO2002005; NO311760; NO984503; NZ332008; OA11176; PL188816; PL329046; PT889880; SK132298; SK282346; TR199801954; TW434239; UA49880; UY24504; WO9736874; ZA972686
Description:

Invenţia se referă la monometansulfonat de acid (E)-alfa-[2-n-butil-1-[(4-carboxifenil)metil-1H-imidazol-5-il]metilen-2-tiofenpropionic în formă dihidrat, la procedeele de preparare a acestuia, în formă dihidrat, la compoziţii care conţin acest compus, precum şi la utilizarea acestuia pentru blocarea receptorilor angiotensinei II şi tratamentul hipertensiunii, a insuficienţei cardiace congestive şi insuficienţei renale.

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