DERIVAT DE DECAHIDROIZOCHINOLINĂ, COMPOZIŢIE FARMACEUTICĂ ŞI UTILIZARE

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Interest:

Assignment

Publication info:

No.: RO119363

Date: 30.08.2004

Inventor(s):

DRESSMAN BRUCE A [US]

FRITZ JAMES E [US]

HAMMOND MARLYS [US]

HORNBACK WILLIAM J [US]

KALDOR STEPHEN W [US]

KALISH VINCENT J [US]

MUNROE JOHN E [US]

REICH SIEGFRIED HEINZ [US]

TATLOCK JOHN H [US]

SHEPHERD TIMOTHY A [US]

RODRIGUEZ MICHAEL J [US]

JUNGHEIM LOUIS N [US]

Applicant(s):
AGOURON PHARMA [US]
Classification:
International patent classification (IPC):
A61K31/00; A61K31/165; A61K31/33; A61K31/40; A61K31/403; A61K31/404; A61K31/435; A61K31/4353; A61K31/4365; A61K31/4427; A61K31/4433; A61K31/445; A61K31/4465; A61K31/47; A61K31/472; A61K31/4725; A61K31/4738; A61K31/4743; A61K31/495; A61K31/535; A61K31/5375; A61K31/675; A61P29/00; A61P31/00; A61P31/12; A61P31/18; A61P43/00; C07C237/42; C07C323/42; C07C323/60; C07D207/16; C07D209/08; C07D211/60; C07D211/62; C07D213/40; C07D213/56; C07D213/81; C07D215/48; C07D215/50; C07D217/02; C07D217/06; C07D217/26; C07D233/66; C07D233/90; C07D295/20; C07D295/205; C07D401/06; C07D401/12; C07D401/14; C07D403/12; C07D403/14; C07D409/12; C07D417/12; C07D471/04; C07D495/04; C07F9/12; C07F9/62; C07K5/00

Cooperative patent classification (CPC):
A61P29/00 (EP); A61P31/00 (EP); A61P31/12 (EP); A61P31/18 (EP); A61P43/00 (EP); C07C237/42 (EP); C07C323/60 (EP); C07D207/16 (EP); C07D209/08 (EP); C07D211/60 (EP); C07D213/40 (EP); C07D215/48 (EP); C07D215/50 (EP); C07D217/02 (EP); C07D217/06 (EP); C07D217/26 (EP); C07D401/06 (EP); C07D401/12 (EP); C07D403/14 (EP); C07D409/12 (EP); C07D417/12 (EP); C07D495/04 (EP); C07F9/62 (EP)
Application info:
No.: RO19960000738
Date: 07.10.1994
Priority number(s):
US19930133543 07.10.1993 ; US19930133696 07.10.1993 ; US19940190764 02.02.1994 ; WO1994US11307 07.10.1994
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AP600; ATE222240; ATE286025; ATE362918; AU694746; AU7967494; BG100455; BG62567; BR9407782; CA2173328; CA2268709; CN1046269; CN1131942; CN1195737; CN1262272; CZ100496; CZ290417; DE69431193; DE69434214; DE69434977; DK0722439; DK0889036; EE05399; EE9600091; EP0722439; EP0889036; EP1340744; ES2181725; ES2236849; ES2287387; FI114794; FI961449; GEP20002209; GEP20084497; HK1013650; HK1014950; HK1056172; HU226814; HU227885; HUT75652; JP2951724; JP3703647; JPH09501443; JPH11310573; KR100190517; MD1507; MY138860; NO307050; NO961382; NZ275633; NZ329626; OA10718; PL185647; PL313871; PT722439; PT889036; RU2139280; SI0722439; SI0889036; SK284115; SK284116; SK43996; TJ339; TW432049; UA56984; US2002077338; US2003216569; US5484926; US5824688; US5827858; US5827859; US5827891; US5834467; US5837710; US5852043; US5859002; US5952343; US6162812; US6271235; US6525215; US6693199; UY23840; WO9509843
Description:

Prezenta invenţie se referă la un derivat de decahidroizochinolină, la compoziţia farmaceutică care îl conţine şi la utilizarea sa ca agent antiviral. Compusul conform invenţiei inhibă sau blochează activitatea proteazei HIV, provocând replicarea virusului HIV. Derivatul de decahidroizochinolină şi compoziţia farmaceutică, care îl conţine, sunt agenţi antivirali. ŕ