Patents

Description

FORME CRISTALINE ALE SĂRII SEMICALCICE A ACIDULUI| [(R-(R*, R*)]-2-(4-FLUOROFENIL)-BETA-DELTA-DIHIDROXI-5-(1-METILETIL)-3-FENIL-4-[(FENILAMINO)CARBONIL]-1H-PIROL-1-HEPTANOIC (ATORVASTATIN)

Price not visible for this package

Interest:

Assignment

Publication info:

No.: RO120070

Date: 30.08.2005

Inventor(s):

BRIGGS CHRISTOPHER A [US]

JENNINGS REX ALLEN [US]

WADE ROBERT A [US]

HARASAWA KIKUKO [JP]

ICHIKAWA SHIGERU [JP]

MINOHARA KAZUO [JP]

NAKAGAWA SHINSUKE [JP]

Applicant(s):
WARNER LAMBERT CO [US]
Classification:
International patent classification (IPC):
A61K31/40; A61P3/06; A61P3/14; A61P43/00; C07D207/34; A61K31/00; C07D
Cooperative patent classification (CPC):
A61P3/06 (EP); A61P3/14 (EP); A61P43/00 (EP); C07D207/34 (EP, KR)
Application info:
No.: RO19980000061
Date: 08.07.1996
Priority number(s):
US19950001452P 17.07.1995 ; WO1996US11368 08.07.1996
Related patents:
AR003458; AR003459; AT8453; ATE208375; ATE284868; AU6484296; AU725424; BG102187; BG63630; BR9609872; CA2220018; CN1087288; CN1190955; CO4700443; CY2358; CZ12198; CZ294108; CZ294695; CZ294740; DE69616808; DE69634054; DK0848705; DK1148049; EA000474; EA199800130; EE03606; EE9800015; EP0848705; EP1148049; ES2167587; ES2233526; GEP20002029; HK1018052; HRP960339; HU223599; HU9900678; IL122118; IL128862; IL128864; IL128865; JP2003073353; JP2011195592; JP2014051533; JP3296564; JP4790194; JPH11509230; KR100389518; KR100431038; KR19990029043; KR20030097628; MX9709099; NO309898; NO980207; NZ312907; PE1898; PL193479; PL324496; PT1148049; PT848705; SI0848705; SI1148049; SK284202; SK6298; TW486467; UA51661; US5969156; UY24285; UY24985; WO9703959; ZA966044
Description:

Invenţia se referă la forme cristaline ale sării semicalcice a acidului [(R-(R*, R*)]-2-(4-fluorofenil)-beta-delta-dihidroxi-5-(1-metiletil)-3-fenil-4-[(fenilamino)carbonil]-1H-pirol-1-heptanoic (atorvastatin), utilizate ca produse farmaceutice, denumite Forma I, Forma II şi Forma IV, care sunt definite prin modelul de difracţie cu raze X a pulberii şi/sau prin determinări de Rezonanţă Magnetică Nucleară, precum şi la procedee de preparare a acestora, la compoziţii farmaceutice, care le conţin, şi la utilizarea lor, ca agenţi hipolipidemici şi hipocolesterolemici. ŕ

Share this on:
Facebook Twitter/X LinkedIn Whatsapp Email