Patents

Description

SARE A UNUI DERIVAT MACROCICLIC DE BIS-INDOLMALEINIMIDĂ, CA INHIBITOR AL PROTEIN KINAZEI C

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Interest:

Assignment

Publication info:

No.: RO120074

Date: 30.08.2005

Inventor(s):

ENGEL GARY L [US]

FARID NAGY A [US]

FAUL MARGARET M [US]

JIROUSEK MICHAEL R [US]

RICHARDSON LORI A [US]

WINNEROSKI LEONARD L JR [US]

Applicant(s):
LILLY CO ELI [US]
Classification:
International patent classification (IPC):
A61K31/395; A61K31/40; A61K31/407; A61K31/44; A61P3/08; A61P3/10; A61P43/00; C07D471/04; C07D498/22; C07D413/14
Cooperative patent classification (CPC):
A61K31/40 (KR); A61P17/00 (EP); A61P25/00 (EP); A61P25/04 (EP); A61P29/00 (EP); A61P3/08 (EP); A61P3/10 (EP); A61P35/00 (EP); A61P43/00 (EP); A61P5/48 (EP); A61P9/00 (EP); A61P9/10 (EP); C07D413/14 (KR); C07D498/22 (EP, US)
Application info:
No.: RO19980000955
Date: 18.11.1996
Priority number(s):
US19950006970P 20.11.1995 ; WO1996US18512 18.11.1996
Related patents:
AR004336; AR004717; ATE172199; AU1054897; AU711125; BR9611724; CA2237221; CN1093759; CN1202825; CO4750823; CY2103; CZ150298; CZ297524; DE69600784; DK0776895; EA000967; EA199800374; EG23871; EP0776895; ES2122764; HU226821; HU9903377; IL124417; JP3348859; JPH11500149; KR100304210; KR19990067596; MX9803792; MY118068; NO310196; NO982182; NZ323571; PE22798; PL184715; PL326754; SI0776895; TR199800759; TW403754; UA61897; US5710145; US6015807; US6117861; WO9718809; YU49315; YU60996; ZA969646
Description:

Prezenta invenţie se referă la o sare a unui derivat macrociclic de bis-indolmaleinimidă, cu formula: şi la solvaţii corespunzători. Invenţia se referă, de asemenea, la o formulare farmaceutică, conţinând sarea unui derivat macrociclic de bis-indolmaleinimidă, la un procedeu de preparare a acestui compus, precum şi la utilizarea acestui compus, pentru inhibarea protein kinazei C, la mamifere. ŕ

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