DERIVAŢI SUBSTITUIŢI DE PIPERIDINĂ, COMPOZIŢII FARMACEUTICE CARE ÎI CONŢIN ŞI UTILIZAREA ACESTORA CA ANTIPSIHOTICE ŞI ANALGEZICE

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Assignment

Publication info:

No.: RO120341

Date: 30.12.2005

Inventor(s):

STRUPCZEWSKI JOSEPH [US]

HELSLEY C GROVER [US]

GLAMKOWSKI J EDWARD [US]

CHIANG YULIN [US]

BORDEAU J KENNETH [US]

NEMOTO PETER A [US]

TEGELER JOHN J [US]

Applicant(s):
HOECHST ROUSSEL PHARMA [US]
Classification:
International patent classification (IPC):
A61K31/415; A61K31/42; A61K31/425; A61K31/44; A61K31/4427; A61K31/445; A61K31/4453; A61K31/47; A61K31/495; A61K31/496; A61K31/505; A61K31/55; A61P23/00; A61P25/00; A61P25/04; A61P25/18; C07C233/25; C07C233/33; C07C255/54; C07C323/22; C07C45/45; C07C45/67; C07C45/71; C07C49/84; C07D207/08; C07D221/04; C07D231/56; C07D239/02; C07D261/20; C07D275/04; C07D275/06; C07D277/82; C07D401/00; C07D401/04; C07D401/12; C07D401/14; C07D403/00; C07D403/04; C07D403/12; C07D403/14; C07D405/04; C07D413/04; C07D413/12; C07D413/14; C07D417/00; C07D417/04; C07D417/14; C07D419/00; C07D471/04; C07F7/18

Cooperative patent classification (CPC):
A61K31/41 (KR); A61K31/495 (KR); A61P23/00 (EP); A61P25/00 (EP); A61P25/04 (EP); A61P25/18 (EP); A61P29/00 (EP); C07C233/25 (EP); C07C233/33 (EP); C07C255/54 (EP); C07C323/22 (EP); C07C45/45 (EP); C07C45/673 (EP); C07C45/71 (EP); C07D207/08 (EP); C07D231/56 (EP); C07D261/20 (EP); C07D275/04 (EP); C07D275/06 (EP); C07D277/82 (EP); C07D401/04 (EP); C07D401/12 (EP); C07D401/14 (EP); C07D403/12 (EP); C07D413/04 (EP); C07D413/12 (EP); C07D413/14 (EP); C07D417/04 (EP, KR); C07D417/14 (EP); C07D471/04 (EP); C07F7/1804 (EP); C07C45/45; C07C49/84; C07C45/673; C07C45/71; C07C47/575; C07C49/755
Application info:
No.: RO19960000888
Date: 27.10.1994
Priority number(s):
US19930144265 28.10.1993 ; US19940329000 25.10.1994 ; WO1994US12054 27.10.1994
Related patents:
AU8122894; CA2175212; CN1136275; CN1143675; CZ123896; CZ295927; EP0730452; EP2311824; JPH09511215; KR100743848; KR100795867; KR20040004478; KR960705819; NO306994; NO961686; NZ275941; PL181059; PL314135; RU2216545; US5550130; US5552414; US5554614; US5556858; US5559116; US5559117; US5559126; US5569653; US5571803; US5571814; US5571828; US5574032; US5578605; US5578624; US5580875; US5580879; US5580886; US5580887; US5580890; US5580891; US5583145; US5589488; US5589494; US5589495; US5591745; US5593995; US5597842; US5599821; US5602158; US5602159; US5605913; US5607945; US5612342; US5612343; US5614543; US5624927; US5629326; US5633265; US5637710; US5639764; US5646161; US5648363; US5652241; US5654319; US5663449; US5776963; US5811430; US5811435; US5840727; US5843949; US5843977; US5854243; US5854263; US5874435; US5889004; US5889035; US5919798; US5965546; US5977113; US5977140; US5998417; US6001834; US6043240; US6110938; US6140345; US6207680; US6251907; US6420390; USRE37029; USRE37478; USRE37729; WO9511680
Description:

Invenţia se referă la următorii derivaţi de piperidină: 1-4-[3-[4-(6-fluoro-1,2-benzizoxazol-3-il)-1-piperidinil]propoxi-3-metoxi-fenil]-2-hidroxietanonă, sau o sare de adiţie acidă corespunzătoare, acceptabilă farmaceutic, 4-[3-[4-(6-fluoro-1,2-benzizoxazol-3-il)-1-piperidinil]propoxi]-2-hidroxi-5-metoxi-alfa-metilbenzenmetanol, sau o sare de adiţie acidă corespunzătoare, acceptabilă farmaceutic şi 1-4-[3-[4-fluoro-1,2-benzizoxazol-3-il)-1-piperidinil]propoxi]-2-hidroxi-5-metoxifenil]etanonă, sau o sare de adiţie acidă corespunzătoare, acceptabilă farmaceutic, la compoziţii farmaceutice, antipsihotice, analgezice şi de depozit, care cuprind aceşti compuşi şi la utilizările acestor compuşi, ca antipsihotice sau analgezice.