Patents

Description

DERIVAŢI DE BENZODIAZEPINĂ, COMPOZIŢII FARMACEUTICE CARE ÎI CONŢIN ŞI UTILIZAREA ACESTORA CA INHIBITORI DE FARNESIL PROTEIN TRANSFERAZĂ

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Interest:

Assignment

Publication info:

No.: RO121118

Date: 29.12.2006

Inventor(s):

DING CHARLES Z [US]

HUNT JOHN T [US]

KIM SOONG HOON [US]

MITT TOOMAS [US]

BHIDE RAJEEV [US]

LEFTHERIS KATERINA [US]

Applicant(s):
BRISTOL MYERS SQUIBB CO [US]
Classification:
International patent classification (IPC):
A61K31/00; A61K31/35; A61K31/4178; A61K31/495; A61K31/498; A61K31/55; A61K31/551; A61K31/5513; A61K31/675; A61P35/00; A61P43/00; C07D243/14; C07D245/06; C07D401/04; C07D401/10; C07D401/14; C07D403/06; C07D403/12; C07D403/14; C07D405/14; C07D407/14; C07D409/14; C07D413/06; C07D413/12; C07D413/14; C07D417/04; C07D417/14; C07D453/02; C07D471/04; C07D473/00; C07D487/04; C07D491/044; C07D491/048; C07D495/04; C07D497/04; C07D513/04; C07F9/645; C07D
Cooperative patent classification (CPC):
A61P35/00 (EP); A61P43/00 (EP); C07D243/14 (EP, KR, US); C07D401/14 (EP, KR, US); C07D403/06 (EP, KR, US); C07D403/14 (EP, KR, US); C07D405/14 (EP, KR, US); C07D409/14 (EP, KR, US); C07D413/14 (EP, KR, US); C07D417/14 (EP, KR, US); C07D471/04 (EP, KR, US); C07D473/00 (EP, KR, US); C07D487/04 (EP, KR, US); C07D495/04 (EP, US)
Application info:
No.: RO19980001326
Date: 24.02.1997
Priority number(s):
US19960012265P 26.02.1996 ; US19960022805P 25.07.1996 ; WO1997US02920 24.02.1997
Related patents:
AU2136697; AU718676; BG102738; BG64951; BR9707614; CA2239187; CN100376569; CN1214685; CN1347881; CZ269698; CZ299762; EE04309; EE9800262; EP0892797; EP1481975; GEP20022616; HU9902016; IL124197; IL141908; JP2000502356; JP4115529; KR100522983; KR19990087250; LV12150; NO319395; NO983892; NZ330287; PL191502; PL328868; RU2225405; SK117398; SK286568; TW496863; UA52642; US6011029; US6455523; WO9730992
Description:

Prezenta invenţie se referă la derivaţi de benzodiazepină, cu formula generală:sau la un enantiomer, diastereomer sau o sare acceptabilă farmaceutic sau un solvat al acestora, la compoziţii farmaceutice care îi conţin şi la utilizarea acestora pentru inhibarea prenil transferazei sau farnesil protein transferazei, fiind utili pentru tratamentul diferitelor forme de cancer.

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