Patents

Description

DERIVAŢI DE ACID PROPIONIC CE INHIBĂ LEGAREA INTEGRINELOR DE RECEPTORII ACESTORA, COMPOZIŢIE FARMACEUTICĂ CE ÎI CONŢINE ŞI UTILIZARE A ACESTEIA

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Interest:

Assignment

Publication info:

No.: RO121640

Date: 30.01.2008

Inventor(s):

BIEDIGER RONALD J [US]

HOLLAND GEORGE W [US]

KASSIR JAMAL M [US]

LI WEN [US]

MARKET ROBERT V [US]

SCOTT IAN L [US]

WU CHENGDE [US]

Applicant(s):
TEXAS BIOTECHNOLOGY CORP [US]
Classification:
International patent classification (IPC):
A61K31/138; A61K31/192; A61K31/33; A61K31/4166; A61K31/4184; A61K31/4412; A61K31/443; A61K31/465; A61K31/497; A61K31/498; A61K31/501; A61K31/505; A61K31/517; A61P1/04; A61P11/06; A61P17/00; A61P19/02; A61P25/00; A61P29/00; A61P3/10; A61P37/06; A61P7/00; A61P9/10; C07C217/48; C07D213/30; C07D213/64; C07D215/02; C07D229/00; C07D235/04; C07D239/36; C07D317/60; C07D405/12; C07D409/14; C07C229/00; C07C233/00
Cooperative patent classification (CPC):
A61P1/04 (EP); A61P11/06 (EP); A61P17/00 (EP); A61P19/02 (EP); A61P25/00 (EP); A61P25/28 (EP); A61P29/00 (EP); A61P3/10 (EP); A61P31/10 (EP); A61P35/00 (EP); A61P35/02 (EP); A61P35/04 (EP); A61P37/06 (EP); A61P37/08 (EP); A61P43/00 (EP); A61P7/00 (EP); A61P9/10 (EP); C07D213/64 (EP, KR); C07D317/60 (EP, KR); C07D405/12 (EP, KR); C07D409/14 (EP, KR)
Application info:
No.: RO20010001209
Date: 05.05.2000
Priority number(s):
US19990132967P 07.05.1999 ; US19990170441P 10.12.1999 ; WO2000US12464 05.05.2000
Related patents:
ATE277923; AU4826900; BR0010349; CA2373180; CN100360499; CN1370143; CZ20013983; CZ304225; DE60014369; EP1189881; ES2228527; HK1044533; HU0202184; HU229155; IL146312; JP2002544187; JP2012006932; JP4841729; JP5468578; KR100767199; KR20020009608; MXPA01011341; NO20015419; NO329899; NZ515249; PL354957; RU2255933; SI20876; SK16092001; SK288186; TR200103427; WO0068188
Description:

Invenţia se referă la derivaţi de acid propionic care inhibă legarea integrinelor de receptoriiacestora, de exemplu VCAM-1 (moleculă tip 1 de adeziune celulară vasculară) ?i fibronectină, la o compoziţie farmaceutică care îi conţine, precum ?i la utilizarea derivaţilor menţionaţi la prepararea unui medicament pentru inhibarea selectivă, la mamifere, a legării integrinei alfa4beta1.

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