Patents

Description

DERIVAŢI PENTACICLICI SUBSTITUIŢI, COMPOZIŢIE FARMACEUTICĂ CE ÎI CONŢINE ŞI UTILIZAREA ACESTORA CA INHIBITORI DE NEURAMINIDAZĂ

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Interest:

Assignment

Publication info:

No.: RO121815

Date: 30.05.2008

Inventor(s):

YARLAGADDA S BABU [US]

POORAN CHAND [US]

MONTGOMERY JOHN A [US]

Applicant(s):
BIOCRYST PHARMACEUTICALS [US]
Classification:
International patent classification (IPC):
A61K31/195; A61K31/196; A61K31/215; A61K31/385; A61K31/4164; A61K31/423; A61P31/12; A61P43/00; C07C229/32; C07C229/48; C07C233/47; C07C247/14; C07C271/24; C07C279/16; C07C279/24; C07C309/66; C07C323/41; C07C323/43; C07C323/59; C07C323/60; C07C49/105; C07C49/297; C07C49/395; C07C61/06; C07C61/20; C07C69/74; C07D233/54; C07D233/56; C07D261/20; C07D339/08; C07D341/00; C07D521/00; A61K; C07C; C07D
Cooperative patent classification (CPC):
A61P31/04 (EP); A61P31/12 (EP); A61P31/16 (EP); A61P43/00 (EP); C07C229/48 (EP, US); C07C233/47 (EP, US); C07C247/14 (EP, US); C07C271/24 (EP, US); C07C279/16 (EP, US); C07C279/24 (EP, US); C07C309/66 (EP, US); C07C323/59 (EP, US); C07C323/60 (EP, US); C07C69/74 (KR); C07D231/12 (EP, US); C07D233/56 (EP, US); C07D249/08 (EP, US); C07D261/20 (EP, US); C07D339/08 (EP, US); C07C2601/08 (EP, US); C07C2601/10 (EP, US)
Application info:
No.: RO19200000635
Date: 17.12.1998
Priority number(s):
US19970069956P 17.12.1997 ; US19980085252P 13.05.1998 ; WO1998US26871 17.12.1998
Related patents:
AR016162; ATE425955; AU2200199; BE2018C032; BR9813480; CA2315262; CN1282316; CY1109153; DK1040094; EP1040094; ES2324746; FR18C1037; HU0100142; JP2001527058; JP2008163035; JP2011256196; JP4102022; JP5118502; JP5709688; KR20010024743; LTC1040094; LTPA2018513; NL300952; NO20003084; PL196674; PL341431; PT1040094; SI1040094; SK8712000; US6562861; WO9933781; ZA9811595
Description:

Invenţia se referă la derivaţi pentaciclici cuformula:în care U este CH, O sau S; Z este C(R2)(R3), CH-N(R2)(R3), C(R3)[(CH2)nR2, CH-C(R3)(R8)(CH2)nR2, C[(CH2)nR2]-[CH(R3)(R8)], C[(R3)][CH[(CH2)nR2](R8)]; R1 este H, (CH2)nOH, (CH2)nNH2, (CH2)nNR10R11, (CH2)nOR11, (CH2)nSR11 sau (CH2)n, la o compoziţie farmaceutică pentru inhibarea neuraminidazei virusului gripal ?i la utilizarea acestora pentru prepararea unui medicament pentru inhibareaneuraminidazei virusului gripal.

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