Patents

Description

DERIVAŢI DE ACID PROPIONIC CE INHIBĂ LEGAREA INTEGRINELOR DE RECEPTORII ACESTORA, COMPOZIŢIE FARMACEUTICĂ CE ÎI CONŢINE ŞI UTILIZARE

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Interest:

Assignment

Publication info:

No.: RO122246

Date: 30.03.2009

Inventor(s):

BIEDIGER RONALD J [US]

CHEN QI [US]

HOLLAND GEORGE W [US]

KASSIR JAMAL M [US]

LI WEN [US]

MARKET ROBERT V [US]

SCOTT IAN L [US]

WU CHENGDE [US]

Applicant(s):
TEXAS BIOTECHNOLOGY CORP [US]
Classification:
International patent classification (IPC):
A61K31/215; A61K31/216; A61K31/335; A61K31/357; A61K31/36; A61K31/38; A61K31/381; A61K31/40; A61K31/4015; A61K31/4025; A61K31/44; A61K31/4409; A61K31/4412; A61K31/4427; A61K31/445; A61K31/4523; A61K31/47; A61K31/506; A61K31/55; A61P1/00; A61P11/06; A61P17/00; A61P19/00; A61P19/02; A61P25/00; A61P29/00; A61P3/10; A61P35/00; A61P35/02; A61P37/06; A61P37/08; A61P43/00; A61P9/10; C07C275/32; C07C275/34; C07C69/66; C07D207/04; C07D207/18; C07D207/416; C07D211/68; C07D211/72; C07D213/02; C07D213/64; C07D213/69; C07D213/73; C07D213/74; C07D213/75; C07D215/00; C07D215/38; C07D221/04; C07D233/96; C07D239/36; C07D239/46; C07D239/47; C07D317/58; C07D333/20; C07D401/06; C07D405/12; C07D409/12; C07D409/14; C07D471/04; C07D487/04
Cooperative patent classification (CPC):
A61P1/00 (EP); A61P11/06 (EP); A61P17/00 (EP); A61P19/00 (EP); A61P19/02 (EP); A61P25/00 (EP); A61P29/00 (EP); A61P3/10 (EP); A61P35/00 (EP); A61P35/02 (EP); A61P37/06 (EP); A61P37/08 (EP); A61P43/00 (EP); A61P9/10 (EP); C07D213/75 (EP); C07D239/47 (EP); C07D405/12 (EP); C07D409/14 (EP)
Application info:
No.: RO20010001210
Date: 05.05.2000
Priority number(s):
US19990132971P 07.05.1999 ; WO2000US12303 05.05.2000
Related patents:
ATE383153; AU5267900; CA2373360; CY1107438; CZ20013963; CZ303312; DE60037726; DK1176956; EP1176956; ES2296625; HK1045805; IL146311; IN1110KON2001; JP2002544161; JP5132855; MXPA01011340; NO20015418; NO324421; NZ515248; PL205322; PL351396; RU2263109; SI20744; SK16082001; SK286696; TR200103178; TR200201920; WO0067746; ZA200108774
Description:

Invenţia se referă la derivaţi de acid propionic ce inhibă legarea integrinei alfa4beta1 de receptorii acesteia, de exemplu VCAM-1 (moleculă tip 1, de adeziune celulară vasculară) şi fibronectină. De asemenea, invenţia se referă la compoziţii farmaceutice care cuprind derivaţii menţionaţi şi la utilizarea acestor derivaţi ca medicament sau pentru fabricarea unui medicament.

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